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For other uses, see. Sildenafil, sold as the can i buy sildenafil maximum dose of sildenafil citrate over maximum dose of sildenafil citrate the counter brand name. Viagra among others, is a medication used to maximum dose of sildenafil citrate treat erectile dysfunction and pulmonary arterial hypertension. 3, its effectiveness for treating sexual dysfunction in women has not been demonstrated. 3, common side effects include headaches and heartburn, as well as flushed skin. Caution is advised in those who have cardiovascular disease. Rare but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing loss. Sildenafil should not be taken by people who take nitrates such as nitroglycerin (glycerin trinitrate as this may result in a severe and potentially fatal drop in blood pressure. 3, sildenafil can i buy sildenafil over the counter acts by inhibiting cGMP-specific phosphodiesterase type 5 (phosphodiesterase 5, PDE5 an enzyme that promotes degradation of can i buy sildenafil over the counter cGMP, which regulates blood flow in the penis. Pfizer scientists, andrew Bell, David Brown, and Nicholas Terrett originally discovered sildenafil as a treatment for various cardiovascular disorders. 4 5, since becoming available in 1998, sildenafil has been a common treatment for erectile dysfunction; its primary competitors are tadalafil (trade name Cialis) and vardenafil (Levitra). Contents Medical uses 50mg tablets of can i buy sildenafil over the counter sildenafil Sexual dysfunction The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus. 6 Antidepressant-associated sexual dysfunction Tentative evidence suggests that sildenafil may help men who experience antidepressant -induced erectile dysfunction. 7 Pulmonary hypertension While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects as of 2014. 8 Raynaud's phenomenon Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes can i buy sildenafil over the counter for people with secondary Raynaud's phenomenon ; 9 10 these drugs have moderate efficacy for reducing the frequency and duration. 9 As of 2016, their role more generally in Raynaud's was not clear. 10 Adverse effects In clinical trials, the most common adverse can i buy sildenafil over the counter effects of sildenafil use included headache, flushing, indigestion, nasal congestion, and impaired vision, including photophobia and blurred vision. 2 Some sildenafil users have complained of seeing everything tinted blue ( cyanopsia ). 11 Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that sildenafil could lead to vision impairment in rare cases 12 and a number of studies have linked sildenafil use with non-arteritic anterior ischemic optic neuropathy. 13 Rare but serious adverse effects found through postmarketing can i buy sildenafil over the counter surveillance include prolonged erections, severe low blood pressure, myocardial infarction (heart attack ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. 2 In October 2007, the FDA announced that the labeling for all can i buy sildenafil over the counter PDE5 inhibitors, maximum dose of sildenafil citrate including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss. 14 Interactions Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity maximum dose of sildenafil citrate of side effects. Those using protease inhibitors are recommended to limit their use of sildenafil to no more than one 25 mg dose every 48 hours.

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El sildenafilo (compuesto que es sildenafil UK-92,480 vendido bajo la marca. Viagra, Revatio y otros, es un frmaco utilizado para tratar la disfuncin erctil y la hipertensin arterial pulmonar (HPP). Originalmente fue desarrollado por cientficos britnicos y luego llevado al mercado por la compaa farmacutica, pfizer. 1, acta mediante la inhibicin de la fosfodiesterasa tipo 5 especfica de, gMP cclico (PDE5 una enzima que promueve la degradacin del GMPc, que regula el flujo de sangre en el pene. Desde su disponibilidad en el ao 1998, el sildenafilo ha sido el principal tratamiento para la disfuncin erctil, sus principales competidores en el mercado son el vardenafilo (Levitra) que es sildenafil y tadalafil (Cialis). Fue inicialmente diseado para su uso en la hipertensin arterial y la angina de pecho. Los primeros ensayos clnicos fueron realizados en el, hospital de Morriston, en, swansea (Gales). Durante los estudios de fase I, realizados bajo la direccin. Ian Osterloh, se sugiri que la droga tena un ligero efecto en la angina, que es sildenafil pero que poda inducir notables erecciones de pene. 3 4, por lo tanto Pfizer decidi comercializarlo para tratar la disfuncin erctil, en lugar de la angina. El frmaco fue patentado en 1996, y aprobado para su uso en disfuncin erctil por la Administracin de Alimentos y Medicamentos de Estados Unidos (FDA) el 27 de marzo de 1998. As se convirti en la primera pastilla aprobada para tratar la disfuncin erctil en los Estados Unidos, y all se ofreci a la venta el mismo. 5 Inmediatamente se convirti en un gran xito: las ventas anuales de Viagra en el perodo superaron los mil millones de dlares. Cita requerida La prensa britnica present a Peter Dunn y Albert Wood, investigadores de Pfizer, como inventores del frmaco, una afirmacin con la que la empresa se muestra en desacuerdo alegando que, aunque sus nombres aparecen al registrar la patente, esto es slo necesario como requisito. 6 A pesar de que el sildenafilo est disponible nicamente por prescripcin mdica, fue anunciada directamente a los consumidores en la TV. (recomendado por el ex senador. Bob Dole y el astro de ftbol Pel ). Numerosos sitios de Internet ofrecen Viagra para su venta despus de una «consulta en lnea» (un mero cuestionario de la red). 7 El nombre «Viagra» se ha hecho tan famoso que muchos falsos afrodisacos ahora se hacen llamar «Viagra herbal» o son presentados en tabletas azules imitando la forma y el color del producto de Pfizer. Viagra tambin se conoce informalmente como «la pastilla azul» o «vitamina uve» entre otros muchos diferentes nombres. 8 En el ao 2000, las ventas de Viagra coparon el 92 del mercado de pldoras prescriptivas para la disfuncin erctil. 9 En 2007, sus ventas descendieron hasta el 50 debido a la competencia con otros frmacos como el tadalafilo (comercializado como Cialis) y el vardenafilo (Levitra 10 as como con sus propias falsificaciones y copias; y de la aparicin de testimonios de pacientes que sufran. 11 12 En febrero de 2007, la empresa Boots the Chemist anunci que haba realizado un estudio para valorar la venta directa que es sildenafil en farmacias sin receta mdica. El estudio se haba hecho en Mnchester (Inglaterra) y se haba dirigido a varones con edades entre los 30 y 65 aos, que compraron hasta cuatro tabletas despus de una consulta con un farmacutico.

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